Chapter-Specific Guidelines: Infectious Diseases through Neoplasms – Key Terms

Life-threatening organ dysfunction caused by a dysregulated host response to infection; coded with specific organism codes (A40–A41). Sepsis with associated acute organ dysfunction; requires additional code R65.20 or R65.21. The original site where a cancer originated. Cancer that has spread (metastasized) from the primary site to another location. Pre-invasive cancer confined to the epithelium without invasion of the basement membrane; codes D00–D09. ICD-10-CM code for asymptomatic HIV infection status (HIV-positive with no symptoms). ICD-10-CM code for Human immunodeficiency virus (HIV) disease; used when patient has confirmed AIDS or HIV-related complications. Reference table in the ICD-10-CM Alphabetic Index organized by anatomical site and neoplasm behavior. A neoplasm classified as D37–D48 when it cannot be determined whether it is benign or malignant. Encounter for antineoplastic chemotherapy; used as principal diagnosis when patient is admitted for chemo treatment. Methicillin-resistant Staphylococcus aureus; a bacterial infection resistant to beta-lactam antibiotics. U09.9; signs/symptoms persisting after the acute COVID-19 infection has resolved.